Which of the following is NOT a common adverse effect of beta-blockers?

Beta-blockers are a class of medications commonly prescribed for various cardiovascular conditions, such as hypertension, heart failure, and arrhythmias. While these drugs are effective, they are also associated with several adverse effects that healthcare providers must monitor.

Bradycardia is a well-known adverse effect of beta-blockers, as these medications work by blocking beta-adrenergic receptors, leading to a reduction in heart rate. Weakness can also be a side effect, likely due to the overall reduction in cardiac output or as a result of decreased physical activity due to fatigue associated with the medication. Depression is recognized as a potential adverse effect of beta-blockers, particularly with chronic use, as they can affect mood-related neurotransmission.

On the other hand, a rash is not commonly associated with beta-blockers. Although any medication can theoretically cause an allergic reaction or skin issue, this is not a typical adverse effect seen in patients taking beta-blockers. Therefore, the correct answer identifies a less common response that does not align with the typical side effect profile of beta-blockers, distinguishing it from the more frequently observed effects like weakness, bradycardia, and depression.